Symbol
Name
ID

Stk11
serine/threonine kinase 11
MGI:1341870

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Gastrointestinal hemorrhage	Intestinal bleeding	Anemia	Iron deficiency anemia	Hepatosplenomegaly
Disease(s) Associated with STK11	Gastrointestinal hemorrhage	Intestinal bleeding	Anemia	Iron deficiency anemia	Hepatosplenomegaly
pancreatic cancer
Peutz-Jeghers syndrome

Mouse Phenotypes

thymus hypoplasia

enlarged spleen

abnormal bone marrow cell morphology/development

decreased bone marrow cell number

decreased erythrocyte cell number

thrombocytopenia

decreased leukocyte cell number

decreased hematopoietic stem cell number

pancytopenia

increased hematopoietic stem cell number

abnormal bone marrow cell physiology

Availability

Mouse Genotype

Stk11^tm1.1Mlfr/Stk11⁺

Stk11^tm1.1Sjm/Stk11^tm1.1Sjm
Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/0 (conditional)

Stk11^tm1.1Sjm/Stk11^tm1.1Sjm
Tg(Mx1-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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